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IL-15 promotes human myogenesis and mitigates the detrimental effects of TNFα on myotube development

Studies in murine cell lines and in mouse models suggest that IL-15 promotes myogenesis and may protect against the inflammation-mediated skeletal muscle atrophy which occurs in sarcopenia and cachexia. The effects of IL-15 on human skeletal muscle growth and development remain largely uncharacteris...

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Detalles Bibliográficos
Autores principales: O’Leary, Mary F., Wallace, Graham R., Bennett, Andrew J., Tsintzas, Kostas, Jones, Simon W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636823/
https://www.ncbi.nlm.nih.gov/pubmed/29021612
http://dx.doi.org/10.1038/s41598-017-13479-w