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IL-15 promotes human myogenesis and mitigates the detrimental effects of TNFα on myotube development
Studies in murine cell lines and in mouse models suggest that IL-15 promotes myogenesis and may protect against the inflammation-mediated skeletal muscle atrophy which occurs in sarcopenia and cachexia. The effects of IL-15 on human skeletal muscle growth and development remain largely uncharacteris...
Autores principales: | O’Leary, Mary F., Wallace, Graham R., Bennett, Andrew J., Tsintzas, Kostas, Jones, Simon W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636823/ https://www.ncbi.nlm.nih.gov/pubmed/29021612 http://dx.doi.org/10.1038/s41598-017-13479-w |
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