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Soft sensor for monitoring biomass subpopulations in mammalian cell culture processes

OBJECTIVES: Biomass subpopulations in mammalian cell culture processes cause impurities and influence productivity, which requires this critical process parameter to be monitored in real-time. RESULTS: For this reason, a novel soft sensor concept for estimating viable, dead and lysed cell concentrat...

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Detalles Bibliográficos
Autores principales: Kroll, Paul, Stelzer, Ines V., Herwig, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636862/
https://www.ncbi.nlm.nih.gov/pubmed/28786039
http://dx.doi.org/10.1007/s10529-017-2408-0