Identification of PTPN1 as a novel negative regulator of the JNK MAPK pathway using a synthetic screening for pathway-specific phosphatases

The mitogen activated protein kinase (MAPK) signaling cascades transmit extracellular stimulations to generate various cellular responses via the sequential and reversible phosphorylation of kinases. Since the strength and duration of kinase phosphorylation within the pathway determine the cellular...

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Detalles Bibliográficos
Autores principales: Moon, Jiyoung, Ha, Jain, Park, Sang-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636874/
https://www.ncbi.nlm.nih.gov/pubmed/29021559
http://dx.doi.org/10.1038/s41598-017-13494-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636874/
https://www.ncbi.nlm.nih.gov/pubmed/29021559
http://dx.doi.org/10.1038/s41598-017-13494-x

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