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Novel mechanism of regulation of the 5-lipoxygenase/leukotriene B(4) pathway by high-density lipoprotein in macrophages

High-density lipoprotein (HDL) interacts with various cells, particularly macrophages, in functional cell-HDL interactions. Here, we found that HDL protein quality and lipid quality play critical roles in HDL functions. HDL fractions from healthy volunteers (HDL(Healthy)) and patients with recurrent...

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Detalles Bibliográficos
Autores principales: Tsuda, Shigeyasu, Shinohara, Masakazu, Oshita, Toshihiko, Nagao, Manabu, Tanaka, Nobuaki, Mori, Takeshige, Hara, Tetsuya, Irino, Yasuhiro, Toh, Ryuji, Ishida, Tatsuro, Hirata, Ken-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636875/
https://www.ncbi.nlm.nih.gov/pubmed/29021582
http://dx.doi.org/10.1038/s41598-017-13154-0