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Novel mechanism of regulation of the 5-lipoxygenase/leukotriene B(4) pathway by high-density lipoprotein in macrophages
High-density lipoprotein (HDL) interacts with various cells, particularly macrophages, in functional cell-HDL interactions. Here, we found that HDL protein quality and lipid quality play critical roles in HDL functions. HDL fractions from healthy volunteers (HDL(Healthy)) and patients with recurrent...
Autores principales: | Tsuda, Shigeyasu, Shinohara, Masakazu, Oshita, Toshihiko, Nagao, Manabu, Tanaka, Nobuaki, Mori, Takeshige, Hara, Tetsuya, Irino, Yasuhiro, Toh, Ryuji, Ishida, Tatsuro, Hirata, Ken-ichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636875/ https://www.ncbi.nlm.nih.gov/pubmed/29021582 http://dx.doi.org/10.1038/s41598-017-13154-0 |
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