The autophagy scaffold protein ALFY is critical for the granulocytic differentiation of AML cells

Acute myeloid leukemia (AML) is a malignancy of myeloid progenitor cells that are blocked in differentiation. Acute promyelocytic leukemia (APL) is a rare form of AML, which generally presents with a t(15;17) translocation causing expression of the fusion protein PML-RARA. Pharmacological doses of a...

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Detalles Bibliográficos
Autores principales: Schläfli, Anna M., Isakson, Pauline, Garattini, E., Simonsen, Anne, Tschan, Mario P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636880/
https://www.ncbi.nlm.nih.gov/pubmed/29021535
http://dx.doi.org/10.1038/s41598-017-12734-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636880/
https://www.ncbi.nlm.nih.gov/pubmed/29021535
http://dx.doi.org/10.1038/s41598-017-12734-4

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