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The autophagy scaffold protein ALFY is critical for the granulocytic differentiation of AML cells
Acute myeloid leukemia (AML) is a malignancy of myeloid progenitor cells that are blocked in differentiation. Acute promyelocytic leukemia (APL) is a rare form of AML, which generally presents with a t(15;17) translocation causing expression of the fusion protein PML-RARA. Pharmacological doses of a...
Autores principales: | Schläfli, Anna M., Isakson, Pauline, Garattini, E., Simonsen, Anne, Tschan, Mario P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636880/ https://www.ncbi.nlm.nih.gov/pubmed/29021535 http://dx.doi.org/10.1038/s41598-017-12734-4 |
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