Plasma-Generated OH Radical Production for Analyzing Three-Dimensional Structure in Protein Therapeutics

Protein three-dimensional structure dynamically changes in solution depending on the presence of ligands and interacting proteins. Methods for detecting these changes in protein conformation include ‘protein footprinting,’ using mass spectrometry. We describe herein a new technique, PLIMB (Plasma In...

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Detalles Bibliográficos
Autores principales: Minkoff, Benjamin B., Blatz, Joshua M., Choudhury, Faraz A., Benjamin, Daniel, Shohet, J. Leon, Sussman, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636892/
https://www.ncbi.nlm.nih.gov/pubmed/29021557
http://dx.doi.org/10.1038/s41598-017-13371-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636892/
https://www.ncbi.nlm.nih.gov/pubmed/29021557
http://dx.doi.org/10.1038/s41598-017-13371-7

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