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LGR5 promotes cancer stem cell traits and chemoresistance in cervical cancer

Cancer stem cells (CSCs), also known as tumor-initiating cells, contribute to tumorigenesis, resistance to chemoradiotherapy and recurrence in human cancers, suggesting targeting CSCs may represent a potential therapeutic strategy. Leucine-rich repeat-containing G-protein-coupled receptor 5 (LGR5) h...

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Detalles Bibliográficos
Autores principales: Cao, Hao-Zhe, Liu, Xiao-Fang, Yang, Wen-Ting, Chen, Qing, Zheng, Peng-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636966/
https://www.ncbi.nlm.nih.gov/pubmed/28880275
http://dx.doi.org/10.1038/cddis.2017.393