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Acceleration of pancreatic tumorigenesis under immunosuppressive microenvironment induced by Reg3g overexpression

Reg3g is a potential risk for pancreatic ductal adenocarcinoma (PDAC). We previously demonstrated that Reg3g promoted pancreatic carcinogenesis via a STAT3 signaling pathway in a murine model of chronic pancreatitis. Whether the immune response is involved in tumorigenesis induced by Reg3g remains u...

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Detalles Bibliográficos
Autores principales: Liu, Xiulan, Zhou, Zhongshi, Cheng, Qi, Wang, Hongjie, Cao, Hui, Xu, Qianqian, Tuo, Yali, Jiang, Li, Zou, You, Ren, Hongyu, Xiang, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636971/
https://www.ncbi.nlm.nih.gov/pubmed/28880262
http://dx.doi.org/10.1038/cddis.2017.424