Small-molecule RL71-triggered excessive autophagic cell death as a potential therapeutic strategy in triple-negative breast cancer

Triple-negative breast cancer (TNBC) has an aggressive phenotype and a poor prognosis owing to the high propensity for metastatic progression and the absence of specific targeted treatment. Here, we revealed that small-molecule RL71 targeting sarco/endoplasmic reticulum calcium-ATPase 2 (SERCA2) exh...

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Detalles Bibliográficos
Autores principales: Gao, Jian, Fan, Minmin, Peng, Shuang, Zhang, Minxia, Xiang, Gang, Li, Xin, Guo, Wenjie, Sun, Yang, Wu, Xuefeng, Wu, Xudong, Liang, Guang, Shen, Yan, Xu, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636988/
https://www.ncbi.nlm.nih.gov/pubmed/28906486
http://dx.doi.org/10.1038/cddis.2017.444

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636988/
https://www.ncbi.nlm.nih.gov/pubmed/28906486
http://dx.doi.org/10.1038/cddis.2017.444

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