Structural Evidence for the Dopamine-First Mechanism of Norcoclaurine Synthase

[Image: see text] Norcoclaurine synthase (NCS) is a Pictet-Spenglerase that catalyzes the first key step in plant benzylisoquinoline alkaloid metabolism, a compound family that includes bioactive natural products such as morphine. The enzyme has also shown great potential as a biocatalyst for the fo...

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Detalles Bibliográficos
Autores principales: Lichman, Benjamin R., Sula, Altin, Pesnot, Thomas, Hailes, Helen C., Ward, John M., Keep, Nicholas H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637010/
https://www.ncbi.nlm.nih.gov/pubmed/28915025
http://dx.doi.org/10.1021/acs.biochem.7b00769

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637010/
https://www.ncbi.nlm.nih.gov/pubmed/28915025
http://dx.doi.org/10.1021/acs.biochem.7b00769

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