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Structural Evidence for the Dopamine-First Mechanism of Norcoclaurine Synthase
[Image: see text] Norcoclaurine synthase (NCS) is a Pictet-Spenglerase that catalyzes the first key step in plant benzylisoquinoline alkaloid metabolism, a compound family that includes bioactive natural products such as morphine. The enzyme has also shown great potential as a biocatalyst for the fo...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American
Chemical Society
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637010/ https://www.ncbi.nlm.nih.gov/pubmed/28915025 http://dx.doi.org/10.1021/acs.biochem.7b00769 |