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Recognition of DNA Supercoil Geometry by Mycobacterium tuberculosis Gyrase

[Image: see text] Mycobacterium tuberculosis encodes only a single type II topoisomerase, gyrase. As a result, this enzyme likely carries out the cellular functions normally performed by canonical gyrase and topoisomerase IV, both in front of and behind the replication fork. In addition, it is the s...

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Detalles Bibliográficos
Autores principales: Ashley, Rachel E., Blower, Tim R., Berger, James M., Osheroff, Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637011/
https://www.ncbi.nlm.nih.gov/pubmed/28921956
http://dx.doi.org/10.1021/acs.biochem.7b00681