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SHCBP1 promotes synovial sarcoma cell metastasis via targeting TGF-β1/Smad signaling pathway and is associated with poor prognosis

BACKGROUND: Our previous studies reported that SHC SH2-domain binding protein 1 (SHCBP1) functions as an oncogene via promoting cell proliferations in synovial sarcoma (SS) cells. However, whether SHCBP1 has any effect on tumor metastasis remains unexplored. METHODS: The expression of SHCBP1 was ana...

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Detalles Bibliográficos
Autores principales: Peng, Changliang, Zhao, Hui, Song, Yan, Chen, Wei, Wang, Xiaoying, Liu, Xiaoli, Zhang, Cheng, Zhao, Jie, Li, Ji, Cheng, Guanghui, Wu, Dongjin, Gao, Chunzheng, Wang, Xiuwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637052/
https://www.ncbi.nlm.nih.gov/pubmed/29020987
http://dx.doi.org/10.1186/s13046-017-0616-z