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Revealing complete complex KIR haplotypes phased by long-read sequencing technology

The killer cell immunoglobulin-like receptor (KIR) region of human chromosome 19 contains up to 16 genes for natural killer (NK) cell receptors that recognize human leukocyte antigen (HLA)/peptide complexes and other ligands. The KIR proteins fulfill functional roles in infections, pregnancy, autoim...

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Detalles Bibliográficos
Autores principales: Roe, D, Vierra-Green, C, Pyo, C-W, Eng, K, Hall, R, Kuang, R, Spellman, S, Ranade, S, Geraghty, D E, Maiers, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637231/
https://www.ncbi.nlm.nih.gov/pubmed/28569259
http://dx.doi.org/10.1038/gene.2017.10