Prediction of a highly deleterious mutation E17K in AKT-1 gene: An in silico approach

The AKT1 (v-akt murine thymoma viral oncogene homologue 1) kinase is a member of most frequently activated proliferation and survival signaling pathway in cancer. Recently, hyperactivation of AKT1, due to functional point mutation in the pleckstrin homology (PH) domain of AKT1 gene, has been found t...

Descripción completa

Detalles Bibliográficos
Autores principales: Khan, Imran, Ansari, Irfan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637233/
https://www.ncbi.nlm.nih.gov/pubmed/29114575
http://dx.doi.org/10.1016/j.bbrep.2017.04.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637233/
https://www.ncbi.nlm.nih.gov/pubmed/29114575
http://dx.doi.org/10.1016/j.bbrep.2017.04.013

Ejemplares similares