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The prognostic value of C-X-C motif chemokine receptor 4 in patients with sporadic malignant peripheral nerve sheath tumors

BACKGROUND: Recent studies indicate that C-X-C motif chemokine receptor 4 (CXCR4) and its ligand, C-X-C motif chemokine ligand 12 (CXCL12), stimulate expression of the cell cycle regulatory protein Cyclin D1 in neurofibromatosis 1-associated malignant peripheral nerve sheath tumor (MPNST) cells and...

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Detalles Bibliográficos
Autores principales: Zhang, Chao, Chang, Fang-Yuan, Zhou, Wen-Ya, Yang, Ji-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637246/
https://www.ncbi.nlm.nih.gov/pubmed/29020982
http://dx.doi.org/10.1186/s40880-017-0246-z