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Collagen triple helix repeat containing 1 (CTHRC1) activates Integrin β3/FAK signaling and promotes metastasis in ovarian cancer

BACKGROUND: Metastasis is the major cause of morbidity and mortality in patients with epithelial ovarian cancer (EOC), however the mechanisms that underline this process are poorly understood. Collagen triple helix repeat containing-1 (CTHRC1) is a 28-kDa secreted protein reported to be involved in...

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Detalles Bibliográficos
Autores principales: Guo, Biying, Yan, Huan, Li, Luying, Yin, Kemin, Ji, Fang, Zhang, Shu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637322/
https://www.ncbi.nlm.nih.gov/pubmed/29021002
http://dx.doi.org/10.1186/s13048-017-0358-8