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Improved scFv Anti-LOX-1 Binding Activity by Fusion with LOX-1-Binding Peptides

The oxidized low-density lipoprotein receptor-1 (LOX-1) targeted single-chain variable fragment (scFvs) is a promising molecule for the targeted delivery of imaging and therapeutic molecules of atherosclerotic diseases; however, its applications are limited by the inherent low antigen affinity. In t...

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Detalles Bibliográficos
Autores principales: Hu, Wei, Xie, Qiuhong, Xiang, Hongyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637825/
https://www.ncbi.nlm.nih.gov/pubmed/29094051
http://dx.doi.org/10.1155/2017/8946935