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Improved scFv Anti-LOX-1 Binding Activity by Fusion with LOX-1-Binding Peptides
The oxidized low-density lipoprotein receptor-1 (LOX-1) targeted single-chain variable fragment (scFvs) is a promising molecule for the targeted delivery of imaging and therapeutic molecules of atherosclerotic diseases; however, its applications are limited by the inherent low antigen affinity. In t...
Autores principales: | Hu, Wei, Xie, Qiuhong, Xiang, Hongyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637825/ https://www.ncbi.nlm.nih.gov/pubmed/29094051 http://dx.doi.org/10.1155/2017/8946935 |
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