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Generation and Bioenergetic Profiles of Cybrids with East Asian mtDNA Haplogroups

Human mitochondrial DNA (mtDNA) variants and haplogroups may contribute to susceptibility to various diseases and pathological conditions, but the underlying mechanisms are not well understood. To address this issue, we established a cytoplasmic hybrid (cybrid) system to investigate the role of mtDN...

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Detalles Bibliográficos
Autores principales: Zhou, Huaibin, Nie, Ke, Qiu, Ruyi, Xiong, Jingting, Shao, Xiaoli, Wang, Bingqian, Shen, Lijun, Lyu, Jianxin, Fang, Hezhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637837/
https://www.ncbi.nlm.nih.gov/pubmed/29093766
http://dx.doi.org/10.1155/2017/1062314