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SOX11 promotes invasive growth and ductal carcinoma in situ progression

Here, we show that SOX11, an embryonic mammary marker that is normally silent in postnatal breast cells, is expressed in many oestrogen receptor‐negative preinvasive ductal carcinoma in situ (DCIS) lesions. Mature mammary epithelial cells engineered to express SOX11 showed alterations in progenitor...

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Detalles Bibliográficos
Autores principales: Oliemuller, Erik, Kogata, Naoko, Bland, Philip, Kriplani, Divya, Daley, Frances, Haider, Syed, Shah, Vandna, Sawyer, Elinor J, Howard, Beatrice A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637904/
https://www.ncbi.nlm.nih.gov/pubmed/28707729
http://dx.doi.org/10.1002/path.4939