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Regulation of Rab5 isoforms by transcriptional and post‐transcriptional mechanisms in yeast

Rab5 GTPases are master regulators of early endosome biogenesis and transport. The genome of Saccharomyces cerevisiae encodes three Rab5 proteins: Vps21, the major isoform, Ypt52 and Ypt53. Here, we show that Vps21 is the most abundant Rab5 protein and Ypt53 is the least abundant. In stressed cells,...

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Detalles Bibliográficos
Autores principales: Schmidt, Oliver, Weyer, Yannick, Fink, Matthias J., Müller, Martin, Weys, Sabine, Bindreither, Marietta, Teis, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637908/
https://www.ncbi.nlm.nih.gov/pubmed/28792590
http://dx.doi.org/10.1002/1873-3468.12785