Cargando…
Hierarchical probabilistic models for multiple gene/variant associations based on next-generation sequencing data
MOTIVATION: The identification of genetic variants influencing gene expression (known as expression quantitative trait loci or eQTLs) is important in unravelling the genetic basis of complex traits. Detecting multiple eQTLs simultaneously in a population based on paired DNA-seq and RNA-seq assays em...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637939/ https://www.ncbi.nlm.nih.gov/pubmed/28575251 http://dx.doi.org/10.1093/bioinformatics/btx355 |