Hierarchical probabilistic models for multiple gene/variant associations based on next-generation sequencing data

MOTIVATION: The identification of genetic variants influencing gene expression (known as expression quantitative trait loci or eQTLs) is important in unravelling the genetic basis of complex traits. Detecting multiple eQTLs simultaneously in a population based on paired DNA-seq and RNA-seq assays em...

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Detalles Bibliográficos
Autores principales: Vavoulis, Dimitrios V, Taylor, Jenny C, Schuh, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637939/
https://www.ncbi.nlm.nih.gov/pubmed/28575251
http://dx.doi.org/10.1093/bioinformatics/btx355

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