DNA Cross-Bridging Shapes a Single Nucleus from a Set of Mitotic Chromosomes

Eukaryotic cells store their chromosomes in a single nucleus. This is important to maintain genomic integrity, as chromosomes packaged into separate nuclei (micronuclei) are prone to massive DNA damage. During mitosis, higher eukaryotes disassemble their nucleus and release individualized chromosome...

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Detalles Bibliográficos
Autores principales: Samwer, Matthias, Schneider, Maximilian W.G., Hoefler, Rudolf, Schmalhorst, Philipp S., Jude, Julian G., Zuber, Johannes, Gerlich, Daniel W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638020/
https://www.ncbi.nlm.nih.gov/pubmed/28841419
http://dx.doi.org/10.1016/j.cell.2017.07.038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638020/
https://www.ncbi.nlm.nih.gov/pubmed/28841419
http://dx.doi.org/10.1016/j.cell.2017.07.038

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