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DNA Cross-Bridging Shapes a Single Nucleus from a Set of Mitotic Chromosomes
Eukaryotic cells store their chromosomes in a single nucleus. This is important to maintain genomic integrity, as chromosomes packaged into separate nuclei (micronuclei) are prone to massive DNA damage. During mitosis, higher eukaryotes disassemble their nucleus and release individualized chromosome...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638020/ https://www.ncbi.nlm.nih.gov/pubmed/28841419 http://dx.doi.org/10.1016/j.cell.2017.07.038 |