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Finding the Sources of Missing Heritability within Rare Variants Through Simulation
Thousands of genome-wide association studies (GWAS) have been conducted to identify the genetic variants associated with complex disorders. However, only a small proportion of phenotypic variances can be explained by the reported variants. Moreover, many GWAS failed to identify genetic variants asso...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638154/ https://www.ncbi.nlm.nih.gov/pubmed/29051702 http://dx.doi.org/10.1177/1177932217735096 |