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Finding the Sources of Missing Heritability within Rare Variants Through Simulation

Thousands of genome-wide association studies (GWAS) have been conducted to identify the genetic variants associated with complex disorders. However, only a small proportion of phenotypic variances can be explained by the reported variants. Moreover, many GWAS failed to identify genetic variants asso...

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Detalles Bibliográficos
Autores principales: Bandyopadhyay, Baishali, Chanda, Veda, Wang, Yupeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638154/
https://www.ncbi.nlm.nih.gov/pubmed/29051702
http://dx.doi.org/10.1177/1177932217735096