Assessing and predicting drug-induced anticholinergic risks: an integrated computational approach

BACKGROUND: Anticholinergic (AC) adverse drug events (ADEs) are caused by inhibition of muscarinic receptors as a result of designated or off-target drug–receptor interactions. In practice, AC toxicity is assessed primarily based on clinician experience. The goal of this study was to evaluate a nove...

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Detalles Bibliográficos
Autores principales: Xu, Dong, Anderson, Heather D., Tao, Aoxiang, Hannah, Katia L., Linnebur, Sunny A., Valuck, Robert J., Culbertson, Vaughn L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638173/
https://www.ncbi.nlm.nih.gov/pubmed/29090085
http://dx.doi.org/10.1177/2042098617725267

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638173/
https://www.ncbi.nlm.nih.gov/pubmed/29090085
http://dx.doi.org/10.1177/2042098617725267

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