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Identifying direct contacts between protein complex subunits from their conditional dependence in proteomics datasets
Determining the three dimensional arrangement of proteins in a complex is highly beneficial for uncovering mechanistic function and interpreting genetic variation in coding genes comprising protein complexes. There are several methods for determining co-complex interactions between proteins, among t...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638211/ https://www.ncbi.nlm.nih.gov/pubmed/29023445 http://dx.doi.org/10.1371/journal.pcbi.1005625 |