Evaluating the efficiency of CHEF and CMV promoter with IRES and Furin/2A linker sequences for monoclonal antibody expression in CHO cells

In recent years, monoclonal antibodies (mAbs) have been developed as powerful therapeutic and diagnostic agents and Chinese hamster ovary (CHO) cells have emerged as the dominant host for the recombinant expression of these proteins. A critical step in recombinant expression is the utilization of st...

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Detalles Bibliográficos
Autores principales: Ebadat, Saeedeh, Ahmadi, Samira, Ahmadi, Maryam, Nematpour, Fatemeh, Barkhordari, Farzaneh, Mahdian, Reza, Davami, Fatemeh, Mahboudi, Fereidoun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638317/
https://www.ncbi.nlm.nih.gov/pubmed/29023479
http://dx.doi.org/10.1371/journal.pone.0185967

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638317/
https://www.ncbi.nlm.nih.gov/pubmed/29023479
http://dx.doi.org/10.1371/journal.pone.0185967

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