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Pancreatic and snake venom presynaptically active phospholipases A(2) inhibit nicotinic acetylcholine receptors

Phospholipases A(2) (PLA(2)s) are enzymes found throughout the animal kingdom. They hydrolyze phospholipids in the sn-2 position producing lysophospholipids and unsaturated fatty acids, agents that can damage membranes. PLA(2)s from snake venoms have numerous toxic effects, not all of which can be e...

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Detalles Bibliográficos
Autores principales: Vulfius, Catherine A., Kasheverov, Igor E., Kryukova, Elena V., Spirova, Ekaterina N., Shelukhina, Irina V., Starkov, Vladislav G., Andreeva, Tatyana V., Faure, Grazyna, Zouridakis, Marios, Tsetlin, Victor I., Utkin, Yuri N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638340/
https://www.ncbi.nlm.nih.gov/pubmed/29023569
http://dx.doi.org/10.1371/journal.pone.0186206