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Regeneration of glycocalyx by heparan sulfate and sphingosine 1-phosphate restores inter-endothelial communication
Vasculoprotective endothelium glycocalyx (GCX) shedding plays a critical role in vascular disease. Previous work demonstrated that GCX degradation disrupts endothelial cell (EC) gap junction connexin (Cx) proteins, likely blocking interendothelial molecular transport that maintains EC and vascular t...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638341/ https://www.ncbi.nlm.nih.gov/pubmed/29023478 http://dx.doi.org/10.1371/journal.pone.0186116 |