Cargando…

Regeneration of glycocalyx by heparan sulfate and sphingosine 1-phosphate restores inter-endothelial communication

Vasculoprotective endothelium glycocalyx (GCX) shedding plays a critical role in vascular disease. Previous work demonstrated that GCX degradation disrupts endothelial cell (EC) gap junction connexin (Cx) proteins, likely blocking interendothelial molecular transport that maintains EC and vascular t...

Descripción completa

Detalles Bibliográficos
Autores principales: Mensah, Solomon A., Cheng, Ming J., Homayoni, Homa, Plouffe, Brian D., Coury, Arthur J., Ebong, Eno E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638341/
https://www.ncbi.nlm.nih.gov/pubmed/29023478
http://dx.doi.org/10.1371/journal.pone.0186116