Cargando…

Regeneration of glycocalyx by heparan sulfate and sphingosine 1-phosphate restores inter-endothelial communication

Vasculoprotective endothelium glycocalyx (GCX) shedding plays a critical role in vascular disease. Previous work demonstrated that GCX degradation disrupts endothelial cell (EC) gap junction connexin (Cx) proteins, likely blocking interendothelial molecular transport that maintains EC and vascular t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mensah, Solomon A., Cheng, Ming J., Homayoni, Homa, Plouffe, Brian D., Coury, Arthur J., Ebong, Eno E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638341/ https://www.ncbi.nlm.nih.gov/pubmed/29023478 http://dx.doi.org/10.1371/journal.pone.0186116

Ejemplares similares

Endothelial Glycocalyx-Mediated Intercellular Interactions: Mechanisms and Implications for Atherosclerosis and Cancer Metastasis
por: Mensah, Solomon A., et al.
Publicado: (2020)

Glycocalyx in Atherosclerosis-Relevant Endothelium Function and as a Therapeutic Target
por: Mitra, Ronodeep, et al.
Publicado: (2017)

Pro-atherosclerotic disturbed flow disrupts caveolin-1 expression, localization, and function via glycocalyx degradation
por: Harding, Ian C., et al.
Publicado: (2018)

Heparan sulfate mimetic fucoidan restores the endothelial glycocalyx and protects against dysfunction induced by serum of COVID-19 patients in the intensive care unit
por: Yuan, Lushun, et al.
Publicado: (2022)

Metastatic cancer cell attachment to endothelium is promoted by endothelial glycocalyx sialic acid degradation
por: Mensah, Solomon A., et al.
Publicado: (2019)

Glomerular endothelial glycocalyx-derived heparan sulfate inhibits glomerular leukocyte influx and attenuates experimental glomerulonephritis
por: Maciej-Hulme, Marissa L., et al.
Publicado: (2023)

Heparan sulfates and heparan sulfate binding proteins in sepsis
por: Liao, Yi-En, et al.
Publicado: (2023)

Glycocalyx engineering with heparan sulfate mimetics attenuates Wnt activity during adipogenesis to promote glucose uptake and metabolism
por: Trieger, Greg W., et al.
Publicado: (2023)

Heparan Sulfate and Heparan Sulfate Proteoglycans in Cancer Initiation and Progression
por: Nagarajan, Arvindhan, et al.
Publicado: (2018)

The Structural Stability of the Endothelial Glycocalyx after Enzymatic Removal of Glycosaminoglycans
por: Zeng, Ye, et al.
Publicado: (2012)

Endothelial glycocalyx conditions influence nanoparticle uptake for passive targeting
por: Cheng, Ming J, et al.
Publicado: (2016)

Combinatorial Roles of Heparan Sulfate Proteoglycans and Heparan Sulfates in Caenorhabditis elegans Neural Development
por: Kinnunen, Tarja K.
Publicado: (2014)

Endothelial glycocalyx sensitivity to chemical and mechanical sub-endothelial substrate properties
por: Hamrangsekachaee, Mohammad, et al.
Publicado: (2023)

Heparan sulfate gets specific
por: Dove, Alan W.
Publicado: (2001)

Heparan sulfate proteoglycans and cancer
por: Blackhall, F H, et al.
Publicado: (2001)

Heparan Sulfate Proteoglycans in Infection
por: Bartlett, Allison H., et al.
Publicado: (2011)

Heparan Sulfate Proteoglycans in Tauopathy
por: Zhu, Yanan, et al.
Publicado: (2022)

Mutations in the heparan sulfate backbone elongating enzymes EXT1 and EXT2 have no major effect on endothelial glycocalyx and the glomerular filtration barrier
por: Khalil, Ramzi, et al.
Publicado: (2022)

A dominant negative splice variant of the heparan sulfate biosynthesis enzyme NDST1 reduces heparan sulfate sulfation
por: Missaghian, Parisa, et al.
Publicado: (2022)

Glycocalyx heparan sulfate cleavage promotes endothelial cell angiopoietin-2 expression by impairing shear stress–related AMPK/FoxO1 signaling
por: Richter, Robert P., et al.
Publicado: (2022)

Ultrasmall gold nanorods: synthesis and glycocalyx-related permeability in human endothelial cells
por: Cheng, Ming J, et al.
Publicado: (2019)

Interaction of microRNAs with sphingosine kinases, sphingosine-1 phosphate, and sphingosine-1 phosphate receptors in cancer
por: Xu, Guangmeng, et al.
Publicado: (2021)

Divergent Synthesis of Heparan Sulfate Oligosaccharides
por: Dulaney, Steven B., et al.
Publicado: (2015)

Heparan sulfate is essential for thymus growth
por: Hsu, Hsuan-Po, et al.
Publicado: (2021)

Dexamethasone Inhibits Heparan Sulfate Biosynthetic System and Decreases Heparan Sulfate Content in Orthotopic Glioblastoma Tumors in Mice
por: Sokolov, Dmitry K., et al.
Publicado: (2023)

The endothelial glycocalyx and its disruption, protection and regeneration: a narrative review
por: Schött, Ulf, et al.
Publicado: (2016)

The Role of Sphingolipids and Sphingosine-1-phosphate—Sphingosine-1-phosphate-receptor Signaling in Psoriasis
por: Masuda-Kuroki, Kana, et al.
Publicado: (2023)

Serum heparan sulfate levels are elevated in endotoxemia
por: Hofmann-Kiefer, KF, et al.
Publicado: (2009)

Heparan Sulfate Biosynthesis: Methods for Investigation of the Heparanosome
por: Multhaupt, Hinke A. B., et al.
Publicado: (2012)

Heparan Sulfate-Dependent Enhancement of Henipavirus Infection
por: Mathieu, Cyrille, et al.
Publicado: (2015)

Heparan Sulfate Proteoglycans in Human Colorectal Cancer
por: Vicente, Carolina Meloni, et al.
Publicado: (2018)

Synaptogenesis Is Modulated by Heparan Sulfate in Caenorhabditis elegans
por: Lázaro-Peña, María I., et al.
Publicado: (2018)

Profiling Heparan Sulfate Proteoglycans in Ovarian Carcinoma
por: Clamp, Andrew R., et al.
Publicado: (2005)

Spotlight on the Transglutaminase 2-Heparan Sulfate Interaction
por: Furini, Giulia, et al.
Publicado: (2019)

Heparan sulfate proteoglycans regulate autophagy in Drosophila
por: Reynolds-Peterson, Claire E., et al.
Publicado: (2017)

Heparan Sulfate Proteoglycan Signaling in Tumor Microenvironment
por: De Pasquale, Valeria, et al.
Publicado: (2020)

Heparan sulfate functions are altered in the osteoarthritic cartilage
por: Shamdani, Sara, et al.
Publicado: (2020)

Heparan Sulfate Biosynthesis and Sulfation Profiles as Modulators of Cancer Signalling and Progression
por: Marques, Catarina, et al.
Publicado: (2021)

Differential distribution of heparan sulfate glycoforms and elevated expression of heparan sulfate biosynthetic enzyme genes in the brain of mucopolysaccharidosis IIIB mice
por: McCarty, Douglas M., et al.
Publicado: (2011)

Sphingosine 1-Phosphate and Atherosclerosis
por: Kurano, Makoto, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_vdhl9b853pr7mdi72ar5oagbc0