The hnRNP-like Nab3 termination factor can employ heterologous prion-like domains in place of its own essential low complexity domain

Many RNA-binding proteins possess domains with a biased amino acid content. A common property of these low complexity domains (LCDs) is that they assemble into an ordered amyloid form, juxtaposing RNA recognition motifs in a subcellular compartment in which RNA metabolism is focused. Yeast Nab3 is o...

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Detalles Bibliográficos
Autores principales: Loya, Travis J., O’Rourke, Thomas W., Reines, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638401/
https://www.ncbi.nlm.nih.gov/pubmed/29023495
http://dx.doi.org/10.1371/journal.pone.0186187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638401/
https://www.ncbi.nlm.nih.gov/pubmed/29023495
http://dx.doi.org/10.1371/journal.pone.0186187

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