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The hnRNP-like Nab3 termination factor can employ heterologous prion-like domains in place of its own essential low complexity domain
Many RNA-binding proteins possess domains with a biased amino acid content. A common property of these low complexity domains (LCDs) is that they assemble into an ordered amyloid form, juxtaposing RNA recognition motifs in a subcellular compartment in which RNA metabolism is focused. Yeast Nab3 is o...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638401/ https://www.ncbi.nlm.nih.gov/pubmed/29023495 http://dx.doi.org/10.1371/journal.pone.0186187 |