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Pooled analysis of menstrual irregularities from three major clinical studies evaluating everolimus for the treatment of tuberous sclerosis complex

OBJECTIVES: To determine the impact of everolimus on female fertility, including menstrual irregularities, secondary amenorrhea, and luteinizing and follicle stimulating hormone levels in female patients. DESIGN: A pooled analysis from 3 prospective studies consisting of a core phase (≥6 months) and...

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Detalles Bibliográficos
Autores principales: Sparagana, Steven, Franz, David N., Krueger, Darcy A., Bissler, John J., Berkowitz, Noah, Burock, Karin, Kingswood, J. Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638404/
https://www.ncbi.nlm.nih.gov/pubmed/29023494
http://dx.doi.org/10.1371/journal.pone.0186235