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Cardiac leiomodin2 binds to the sides of actin filaments and regulates the ATPase activity of myosin

Leiomodin proteins are vertebrate homologues of tropomodulin, having a role in the assembly and maintenance of muscle thin filaments. Leiomodin2 contains an N-terminal tropomodulin homolog fragment including tropomyosin-, and actin-binding sites, and a C-terminal Wiskott-Aldrich syndrome homology 2...

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Detalles Bibliográficos
Autores principales: Szatmári, Dávid, Bugyi, Beáta, Ujfalusi, Zoltán, Grama, László, Dudás, Réka, Nyitrai, Miklós
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638494/
https://www.ncbi.nlm.nih.gov/pubmed/29023566
http://dx.doi.org/10.1371/journal.pone.0186288