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Polymorphism IL-1RN rs419598 reduces the susceptibility to generalized periodontitis in a population of European descent

Interleukin (IL) 1-ra is a potent endogenous competitive inhibitor of IL-α and β and has an anti-inflammatory role. Study objectives were: 1) to assess the associations of IL-1RN genetic single nucleotide polymorphism (SNP) (rs419598) with generalized chronic periodontitis (GCP), generalized aggress...

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Detalles Bibliográficos
Autores principales: Mesa, Francisco, Lanza, Esperanza, García, Llenalia, Marfil-Alvarez, Rafael, Magan-Fernandez, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638498/
https://www.ncbi.nlm.nih.gov/pubmed/29023524
http://dx.doi.org/10.1371/journal.pone.0186366