Despite disorganized synapse structure, Th2 cells maintain directional delivery of CD40L to antigen-presenting B cells

Upon recognition of peptide displayed on MHC molecules, Th1 and Th2 cells form distinct immunological synapse structures. Th1 cells have a bull’s eye synapse structure with TCR/ MHC-peptide interactions occurring central to a ring of adhesion molecules, while Th2 cells have a multifocal synapse with...

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Detalles Bibliográficos
Autores principales: Gardell, Jennifer L., Parker, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638602/
https://www.ncbi.nlm.nih.gov/pubmed/29023539
http://dx.doi.org/10.1371/journal.pone.0186573

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638602/
https://www.ncbi.nlm.nih.gov/pubmed/29023539
http://dx.doi.org/10.1371/journal.pone.0186573

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