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Despite disorganized synapse structure, Th2 cells maintain directional delivery of CD40L to antigen-presenting B cells
Upon recognition of peptide displayed on MHC molecules, Th1 and Th2 cells form distinct immunological synapse structures. Th1 cells have a bull’s eye synapse structure with TCR/ MHC-peptide interactions occurring central to a ring of adhesion molecules, while Th2 cells have a multifocal synapse with...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638602/ https://www.ncbi.nlm.nih.gov/pubmed/29023539 http://dx.doi.org/10.1371/journal.pone.0186573 |