IRF-8 regulates expansion of myeloid-derived suppressor cells and Foxp3(+) regulatory T cells and modulates Th2 immune responses to gastrointestinal nematode infection

Interferon regulatory factor-8 (IRF-8) is critical for Th1 cell differentiation and negatively regulates myeloid cell development including myeloid-derived suppressor cells (MDSC). MDSC expand during infection with various pathogens including the gastrointestinal (GI) nematode Heligmosomoides polygy...

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Detalles Bibliográficos
Autores principales: Valanparambil, Rajesh M., Tam, Mifong, Gros, Pierre-Paul, Auger, Jean-Philippe, Segura, Mariela, Gros, Philippe, Jardim, Armando, Geary, Timothy G., Ozato, Keiko, Stevenson, Mary M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638610/
https://www.ncbi.nlm.nih.gov/pubmed/28968468
http://dx.doi.org/10.1371/journal.ppat.1006647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638610/
https://www.ncbi.nlm.nih.gov/pubmed/28968468
http://dx.doi.org/10.1371/journal.ppat.1006647

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