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BMAL1 LINKS THE CIRCADIAN CLOCK TO VIRAL AIRWAY PATHOLOGY AND ASTHMA PHENOTYPES

Patients with asthma experience circadian variations in their symptoms. However it remains unclear how specific aspects of this common airway disease relate to clock genes, which are critical to the generation of circadian rhythms in mammals. Here, we used a viral model of acute and chronic airway d...

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Detalles Bibliográficos
Autores principales: Ehlers, Anna, Xie, Wenfang, Agapov, Eugene, Brown, Samuel, Steinberg, Deborah, Tidwell, Rose, Sajol, Geneline, Schutz, Rebecca, Weaver, Rachel, Yu, Huixi, Castro, Mario, Bacharier, Leonard B., Wang, Xinhua, Holtzman, Michael J., Haspel, Jeffrey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638664/
https://www.ncbi.nlm.nih.gov/pubmed/28401936
http://dx.doi.org/10.1038/mi.2017.24