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Inhibition of the DevSR Two-Component System by Overexpression of Mycobacterium tuberculosis PknB in Mycobacterium smegmatis

The DevSR (DosSR) two-component system, which is a major regulatory system involved in oxygen sensing in mycobacteria, plays an important role in hypoxic induction of many genes in mycobacteria. We demonstrated that overexpression of the kinase domain of Mycobacterium tuberculosis (Mtb) PknB inhibit...

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Detalles Bibliográficos
Autores principales: Bae, Hyun-Jung, Lee, Ha-Na, Baek, Mi-Na, Park, Eun-Jin, Eom, Chi-Yong, Ko, In-Jeong, Kang, Ho-Young, Oh, Jeong-Il
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638771/
https://www.ncbi.nlm.nih.gov/pubmed/28843272
http://dx.doi.org/10.14348/molcells.2017.0076