Evidence of Early-Stage Selection on EPAS1 and GPR126 Genes in Andean High Altitude Populations

The aim of this study is to identify genetic variants that harbour signatures of recent positive selection and may facilitate physiological adaptations to hypobaric hypoxia. To achieve this, we conducted whole genome sequencing and lung function tests in 19 Argentinean highlanders (>3500 m) compa...

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Detalles Bibliográficos
Autores principales: Eichstaedt, Christina A., Pagani, Luca, Antao, Tiago, Inchley, Charlotte E., Cardona, Alexia, Mörseburg, Alexander, Clemente, Florian J., Sluckin, Timothy J., Metspalu, Ene, Mitt, Mario, Mägi, Reedik, Hudjashov, Georgi, Metspalu, Mait, Mormina, Maru, Jacobs, Guy S., Kivisild, Toomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638799/
https://www.ncbi.nlm.nih.gov/pubmed/29026132
http://dx.doi.org/10.1038/s41598-017-13382-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638799/
https://www.ncbi.nlm.nih.gov/pubmed/29026132
http://dx.doi.org/10.1038/s41598-017-13382-4

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