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Arginine methylation catalyzed by PRMT1 is required for B cell activation and differentiation

Arginine methylation catalyzed by protein arginine methyltransferases (PRMT) is a common post-translational modification in mammalian cells, regulating many important functions including cell signalling, proliferation and differentiation. Here we show the role of PRMT1 in B-cell activation and diffe...

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Detalles Bibliográficos
Autores principales: Infantino, Simona, Light, Amanda, O’Donnell, Kristy, Bryant, Vanessa, Avery, Danielle T., Elliott, Michael, Tangye, Stuart G., Belz, Gabrielle, Mackay, Fabienne, Richard, Stephane, Tarlinton, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638811/
https://www.ncbi.nlm.nih.gov/pubmed/29026071
http://dx.doi.org/10.1038/s41467-017-01009-1