Improving membrane protein expression and function using genomic edits

Expression of membrane proteins often leads to growth inhibition and perturbs central metabolism and this burden varies with the protein being overexpressed. There are also known strain backgrounds that allow greater expression of membrane proteins but that differ in efficacy across proteins. We hyp...

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Detalles Bibliográficos
Autores principales: Jensen, Heather M., Eng, Thomas, Chubukov, Victor, Herbert, Robin A., Mukhopadhyay, Aindrila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638813/
https://www.ncbi.nlm.nih.gov/pubmed/29026162
http://dx.doi.org/10.1038/s41598-017-12901-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638813/
https://www.ncbi.nlm.nih.gov/pubmed/29026162
http://dx.doi.org/10.1038/s41598-017-12901-7

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