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Improving membrane protein expression and function using genomic edits
Expression of membrane proteins often leads to growth inhibition and perturbs central metabolism and this burden varies with the protein being overexpressed. There are also known strain backgrounds that allow greater expression of membrane proteins but that differ in efficacy across proteins. We hyp...
Autores principales: | Jensen, Heather M., Eng, Thomas, Chubukov, Victor, Herbert, Robin A., Mukhopadhyay, Aindrila |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638813/ https://www.ncbi.nlm.nih.gov/pubmed/29026162 http://dx.doi.org/10.1038/s41598-017-12901-7 |
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